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Frenchfry

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Re: Health news
« Reply #15 on: July 23, 2012, 03:15:12 AM »

Alzheimer's finding could aid drug hunt
Mutated gene blocks culprit that triggers the brain disease

Two decades ago, researchers began discovering rare gene mutations that cause Alzheimer's disease in all who inherit them. Now, they have found the opposite: a mutation that prevents the devastating brain disorder.

The protective mutation also is very rare; it is not the reason most people do not develop Alzheimer's disease. But what intrigues researchers is how it protects the brain. It does the reverse of what the mutations that cause Alzheimer's do. Those mutations lead to excessive amounts of a normal substance, beta amyloid, in the brain. The protective mutation slows beta amyloid production, so people make much less.

The discovery, published online Wednesday in the journal Nature, provides strong evidence that beta amyloid buildup is a driving force in this destructive brain disease.

It also bolsters the hopes of drug companies that have zealously developed drugs to reduce amyloid levels, with the expectation that they might alter the course of the disease or even prevent it. So far, the drugs have not succeeded, but companies and many researchers have argued that there are reasons for that, and that it is too soon to give up on them.

If for no other reason, the discovery's implication for drug development "is hugely important," said David Altshuler, a genomics expert at Harvard Medical School and the Broad Institute of Harvard and MIT, who was not involved with the research. It indicates, he said, that drug companies' big bets on anti-amyloid treatments could pay off.

"This paper provides strong evidence that it would work in the general population if you did it right," Dr. Altshuler said.

Samuel Gandy, an Alzheimer's researcher who directs the Mount Sinai Center for Cognitive Health, had a similar response, calling the finding "extraordinarily important" -- the field's most significant since 22 years ago, when researchers first reported a mutation that leads to the disease.

Discovery of the protective gene mutation, a result of the revolution that has occurred in genetics, arose when researchers scanned the entire DNA of 1,795 Icelanders. About 1 in 100 had a mutation in the gene for a large protein that is sliced to form beta amyloid.

Then the investigators studied people ages 85 and older and people who had been given an Alzheimer's diagnosis. Those with the mutation seemed protected from Alzheimer's disease.

The investigators, led by Kari Stefansson, chief executive at DeCode Genetics, an Icelandic company, then looked at genomes of North Americans and found the gene mutation in only about 1 in 10,000 people. That indicates, Dr. Stefansson said, that the mutation arose relatively recently in Scandinavia.

The protective gene even appears to override a very strong risk factor for Alzheimer's disease in old age -- two copies of a gene known as ApoE4. Ninety percent of people with two ApoE4 genes get Alzheimer's by age 80. But Dr. Stefansson says there are 25 people in his study with two copies of ApoE4. None has Alzheimer's disease.

The research "is obviously right," said John Hardy, an Alzheimer's researcher at University College London and a discoverer of the first gene mutation found to cause the disease. "The statistics and the finding are pretty secure."

The discovery is part of a continuing story that implicates beta amyloid as a central and crucial player in this destructive brain disease. The idea began two decades ago with discovery of very rare gene mutations that always cause Alzheimer's in those who inherit them, usually by middle age. The mutations were different in different families, but all had the same effect: They increased the amount of beta amyloid in the brain. That meant that a buildup of amyloid was enough to cause the disease.

Elderly people with Alzheimer's -- who typically did not have these gene mutations -- also had excess amyloid in the brain. So, researchers reasoned, that might mean that excess amyloid was causing the disease in them, too.

Additional evidence of the role of beta amyloid was reported Wednesday in The New England Journal of Medicine. Using spinal taps and brain scans to track the protein, investigators found that people with one of the Alzheimer's-causing mutations start making too much beta amyloid as long as 20 years before they have symptoms of the disease.

Researchers and drug companies have focused on the amyloid hypothesis to the extent that almost every experimental drug being tested to slow or halt Alzheimer's disease aims to reduce amyloid in the brain.

But a crucial question remained. Was amyloid really causing Alzheimer's in elderly people? Might the protein instead be a bystander, accumulating, for example, as part of the brain's response to damage?

The discovery of the protective gene mutation provides strong clues. People with the mutation make substantially less beta amyloid, but other than that they are no different from anyone else. And they do not get Alzheimer's.

Many questions remain, of course. Most people do not have the protective gene mutation, but as common as Alzheimer's is, most people do not get it. It is not clear why.

Read more: http://www.post-gazette.com/stories/news/science/alzheimers-finding-could-aid-drug-hunt-644361/#ixzz21QZbeJIs

Article from 2009:
Our results indicate that amyloid beta protein itself isn't the bad guy. The right amount of amyloid beta protein happens to be very important for memory and learning in those who are healthy."

Researchers found that young, healthy mice that received low doses of amyloid beta protein showed improvement in recognizing objects and successfully navigating through a maze. Conversely, mice that received a drug that blocked amyloid beta protein had learning impairment.

"You can't totally wipe out amyloid beta protein. If you do this, you are going to create dementia"
http://www.sciencedaily.com/releases/2009/11/091109194747.htm
« Last Edit: July 23, 2012, 03:21:09 AM by Frenchfry »
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No emails, no warnings, no communication whatsoever...just that ban

May be what happened to the other libs as well.

I guess disabling the report to admin link only on the lib side was indicative of the slanted games they play.

Enjoy your spoon-fed Faux News type right-wing echo-chamber.

Edited to add:

This is the only way to answer some of the questions posed:

1) I did nothing to warrant the banishment, it's political.

2) It's the router that's blocked but considering all the nonsense right-wing games being played by those running the site...it's just not worth it to bypass the banishment block.

3) The moron stalkers from MT contemplating a visit will be considered a threat and can expect to have a bad day if they act upon those idiotic thoughts.

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marilyn.monroe

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Teen Doing Well 2 Years After Stem Cell Windpipe Transplant
« Reply #16 on: July 26, 2012, 10:35:04 AM »

Treatment may offer hope for other ill children, researchers say

WEDNESDAY, July 25 (HealthDay News) -- Two years after he became the first child to receive a stem cell-supported trachea (windpipe) transplant, a 13-year-old boy is able to breathe normally, has grown about four inches taller, does not require any anti-rejection drugs and has returned to school.

Ciaran Finn-Lynch, born with a structural defect of his large airway, underwent the transplant in March 2010 at Great Ormond Street Hospital in London. After his windpipe was removed, it was replaced by a windpipe from a deceased donor in Italy.
 
The windpipe was stripped of the donor's cells down to the inert structure of collagen. Tissue from the lining of Finn-Lynch's windpipe was implanted in the new windpipe to kick-start the growth of a lining in the new windpipe.
 
The surgeons laced the transplanted windpipe with Finn-Lynch's own bone marrow stem cells to prevent his body from rejecting the new organ. The teen also received compounds to promote the growth and differentiation of cells within the new windpipe.

http://health.usnews.com/health-news/news/articles/2012/07/26/teen-doing-well-2-years-after-stem-cell-windpipe-transplant

No embryos required.
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Frenchfry

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Re: Health news
« Reply #17 on: July 26, 2012, 12:35:45 PM »

Faltering Steps May Indicate Oncoming Dementia
3 studies link changes in walking skills to weakening mental state, including Alzheimer's
http://health.usnews.com/health-news/news/articles/2012/07/15/faltering-steps-may-indicate-oncoming-dementia
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This is what I see when I visit:

"Sorry Frenchfry, you are banned from posting and sending personal messages on this forum.
This ban is not set to expire."

No emails, no warnings, no communication whatsoever...just that ban

May be what happened to the other libs as well.

I guess disabling the report to admin link only on the lib side was indicative of the slanted games they play.

Enjoy your spoon-fed Faux News type right-wing echo-chamber.

Edited to add:

This is the only way to answer some of the questions posed:

1) I did nothing to warrant the banishment, it's political.

2) It's the router that's blocked but considering all the nonsense right-wing games being played by those running the site...it's just not worth it to bypass the banishment block.

3) The moron stalkers from MT contemplating a visit will be considered a threat and can expect to have a bad day if they act upon those idiotic thoughts.

bumfunkegypt@live.com

Frenchfry

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Re: Health news
« Reply #18 on: August 11, 2012, 02:50:44 PM »

Woman's hair turns to black fingernails, baffling her doctors
Shanyna Isom has consulted every possible specialist, including a doctor in the Netherlands, but she still as no idea what is wrong with her.

The 28-year-old beautician and former University of Memphis law student has developed a condition so severe, fingernails grow from the hair follicles all over her body.

"Black scabs were coming out of her skin," said her mother, Kathy Gary. "The nails would grow so long and come out and regrow themselves. They are hard to touch and stick you."

The disease so far has affected not only her skin, but her bones and her vision. Because Isom is unable to walk without a cane, her mother helps her out of bed each day.

Doctors at Johns Hopkins Medical Center in Baltimore, where Isom is being treated, told her family that she is the only person in the world with this unknown condition.

And now she has $500,000 in unpaid medical bills. Isom has state insurance, but it doesn't cover medical care in Maryland. Her mother lost her job as a medical receptionist because she looks after her daughter at home, so savings have dried up.

More here:
http://www.kvia.com/news/Woman-s-hair-turns-to-black-fingernails-baffling-her-doctors/-/391068/16057888/-/q0nddtz/-/index.html


Mystery illness causes woman to grow fingernails in place of hair
 What if an unknown illness cost you everything? That is what happened to a Mid-South woman whose medical crisis has baffled doctors for almost three years now.

It is a medical mystery you may find hard to watch, but what this woman lost to disease she has gained in strength and spirit.

Shanyna Isom was a high school graduate working toward a law degree.

"I was in my junior year and I was studying criminal justice," she said.

Today, loved ones have to help her get out of bed or off of the sofa.

"It's almost as if it's a nightmare and you're trying to wake up out of that," she says.

A nightmare that began in September 2009 when Isom had an allergic reaction to steroids she was given for an asthma attack. Within months, she was eaten alive by a debilitating skin disease doctors have yet to diagnose.

"Over time it started to turn my legs black with bumps," Isom said.

Doctors in Memphis treated Isom for everything from eczema to a staph infection.

"And we know it couldn't be that after all the medication she had been on," Shanyna's Aunt, Jataun Isom said.

"They've tested me from A to Z and everything was coming back negative," Shanyna said.

In August 2011 Isom was accepted into Johns Hopkins in Baltimore.

Doctors determined she produces 12 times the number of skin cells per hair follicle, which suffocates her skin.

Instead of hair, her skin follicles produce human nails.

"Where hair grows, nails are growing," she said.

More here:
http://www.msnbc.msn.com/id/48608206/ns/health-womens_health/#.UCapJqOccg9


Doctors baffled by mystery illness which causes woman to grow fingernails instead of hair

    Shanyna Isom's body is covered in hard scabs suffocating her skin
    All hair on her body has been replaced by 'nails'
    Doctors have no clue as to what the disease is or how to cure it
    Treatment has bankrupted her and her family and left her with £160,000 unpaid medical bills

Read more and see the pics here: http://www.dailymail.co.uk/news/article-2185878/Doctors-baffled-mystery-illness-causes-woman-grow-fingernails-instead-hair.html#ixzz23GUuZy7G
« Last Edit: August 11, 2012, 02:52:25 PM by Frenchfry »
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This is what I see when I visit:

"Sorry Frenchfry, you are banned from posting and sending personal messages on this forum.
This ban is not set to expire."

No emails, no warnings, no communication whatsoever...just that ban

May be what happened to the other libs as well.

I guess disabling the report to admin link only on the lib side was indicative of the slanted games they play.

Enjoy your spoon-fed Faux News type right-wing echo-chamber.

Edited to add:

This is the only way to answer some of the questions posed:

1) I did nothing to warrant the banishment, it's political.

2) It's the router that's blocked but considering all the nonsense right-wing games being played by those running the site...it's just not worth it to bypass the banishment block.

3) The moron stalkers from MT contemplating a visit will be considered a threat and can expect to have a bad day if they act upon those idiotic thoughts.

bumfunkegypt@live.com

marilyn.monroe

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Soaring Ointment Prices Are a Dermatologic Mystery
« Reply #19 on: August 12, 2012, 10:53:26 AM »

They are the staples of most dermatology practices: generic creams and ointments that treat everything from skin rashes to athlete’s foot to scabies. Many doctors prescribe the drugs without a second thought. But increasingly, some dermatologists say, patients are complaining about a recent, mysterious and rapid rise in price.

Take betamethasone dipropionate, a cream used to relieve itchy skin. In 2008, a tube cost $18.17. The medicine now costs $71.28, according to Red Book, which tracks wholesale drug prices. Permethrin cream, which kills scabies mites, cost $29.25 in 2008 but has jumped to $71.08 today.

The hefty price increases have stumped doctors and their patients. “It seems to me that something is going on, but I don’t have quantitative details,” said Dr. Steven R. Feldman, a professor of dermatology at Wake Forest Baptist Medical Center in Winston-Salem, N.C. “I wouldn’t have thought that these old-timey, generic drugs would be very costly.”

The phenomenon offers a window into the murky and often illogical world of drug pricing, where prices are not always driven by the usual rules of supply and demand. “In most markets, basic economics would say the lower the price, the higher the volume,” said Les Funtleyder, the health care fund manager for Poliwogg, a private equity and hedge fund. “But health care isn’t one of those standard markets.”

“You might have a lot of itchy people, but people can go around and manage O.K.” Mr. Funtleyder said. “A rash is not a public health emergency.”

That’s not to say the companies aren’t reaping the benefits of the price increases. In a May earnings call, Perrigo’s chairman and chief executive, Joseph C. Papa, told investors that a “favorable pricing environment” in the company’s prescription drug business was one of the reasons prescription net sales increased last quarter by 84 percent. On Monday, Taro reported that net income for the previous quarter had increased to $62.9 million from $35.7 million last year, a 76 percent increase.

$ all about.

http://www.nytimes.com/2012/08/10/business/prescription-skin-creams-jump-in-price.html

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Frenchfry

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Re: Health news
« Reply #20 on: August 13, 2012, 01:41:35 AM »

Spider Found Living In Woman's Ear
"In what can only be described as a nightmare-come-true, a spider crawled inside a woman's ear canal and lived there for five days before doctors extracted it. The woman, referred to only as Ms. Lee, arrived at China's Changsha Central Hospital of Otolaryngology and Head and Neck Surgery on Aug. 8, RedNet News notes. She complained of an itchy ear and was hoping doctors could treat her...".

Spider Found Living In Woman's Ear
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This is what I see when I visit:

"Sorry Frenchfry, you are banned from posting and sending personal messages on this forum.
This ban is not set to expire."

No emails, no warnings, no communication whatsoever...just that ban

May be what happened to the other libs as well.

I guess disabling the report to admin link only on the lib side was indicative of the slanted games they play.

Enjoy your spoon-fed Faux News type right-wing echo-chamber.

Edited to add:

This is the only way to answer some of the questions posed:

1) I did nothing to warrant the banishment, it's political.

2) It's the router that's blocked but considering all the nonsense right-wing games being played by those running the site...it's just not worth it to bypass the banishment block.

3) The moron stalkers from MT contemplating a visit will be considered a threat and can expect to have a bad day if they act upon those idiotic thoughts.

bumfunkegypt@live.com

Monique

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Re: Health news
« Reply #21 on: August 13, 2012, 09:07:36 AM »

Well, that is purely horrifying.
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marilyn.monroe

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Re: Health news
« Reply #22 on: August 14, 2012, 09:05:10 AM »

Well, that is purely horrifying.
I saw that on the web b4 bed. eek. almost put cotton in my ears lol.
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marilyn.monroe

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Are Prescription Drugs Making Us Any Healthier?
« Reply #23 on: August 15, 2012, 08:16:53 AM »

Muscle pain, dizziness, nausea, anxiety, insomnia, coughing, hair loss, fluid retention, liver problems -- these are just a few of the side effects associated with some of the most popular prescription drugs of 2010. These prescriptions include medication for high cholesterol, high blood pressure, low thyroid function, and diabetes. (1)

What's troubling to me is that side effects can happen when taking just one of the drugs. What happens when you're on multiple drugs? Some combinations we already know are dangerous. For example, taking warfarin (a blood thinner) and simvastatin (a cholesterol drug) can increase the risks of bleeding problems. (2) Yet there are many combinations that haven't been studied and when you're on three or four medications; there's 100 percent drug interaction, and you have your own personal experiment

Let's face it. We all want a magic bullet to take our health problems away. But the expectation that a medication is going to simply fix one problem while leaving everything else in the body alone is not the reality. Drugs don't act in a vacuum -- they act system-wide -- which is why we have side effects. For example, the blood pressure drugs known as ACE inhibitors not only relax blood vessels to decrease pressure but constrict pupils, stimulate digestive secretions, and constrict the bronchi in the lungs (which can cause a cough).

And when we take prescriptions every day for years, the body has to constantly work to recalibrate in response. Though it may be lowering blood pressure or cholesterol, for example, these "helpful" changes can be perceived in the body as stress and lead to further health problems down the line, possibly leading to even more medication.

Can We Avoid Prescription Drugs?

Preventing the need for prescription drugs is a multifaceted approach that isn't as easy as popping a pill -- and it doesn't work for every health problem out there. There are certainly situations where prescription drugs are necessary. However, the health benefits that come with trying to avoid prescription drugs when possible are great.

Here are some ideas about how to keep your body healthy so that you can minimize or avoid prescription drugs altogether:

Seek quality nutrition.

Exercise.

Shift to a positive outlook on life.

Reduce stress.

If your practitioner recommends a prescription drug, do your research. Find out what changes you could make in your life to avoid the medication. Talk it over with your doctor and set a time period in which you will try to make changes to your health naturally. The benefits of a natural approach can not only save you money but can contribute to lasting health.

http://www.huffingtonpost.com/marcelle-pick-rnc/prescriptions-health_b_1746525.html

Be good to yourself!
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marilyn.monroe

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Marriage drives women to drink, study says
« Reply #24 on: August 20, 2012, 11:09:47 AM »

http://www.cbsnews.com/8301-205_162-57496285/marriage-drives-women-to-drink-study-says/

(LiveScience) Marriage may drive a woman to drink, not because she's unhappy but because she's influenced by her husband's alcohol consumption, new research suggests. And men, on average, drink more than women.

Men, on the other hand, spend less time with their drinking buddies and more with their wives after tying the knot. The result? Married men down fewer beers than their single counterparts.

The study, being presented at the annual meeting of the American Sociological Association in Denver, Colo., also reveals divorced men are at particularly high risk of alcohol abuse.
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The Fuzz

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Re: Marriage drives women to drink, study says
« Reply #25 on: August 20, 2012, 11:55:00 AM »


Men, on the other hand, spend less time with their drinking buddies and more with their wives after tying the knot. The result? Married men down fewer beers than their single counterparts.


Good read.....I would like to see more of the details on the demographics for the sample size of the selected married couples to come up with the supposition that married people drink less.
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Baggins

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Re: Health news
« Reply #26 on: August 22, 2012, 09:37:45 AM »

Well, that is purely horrifying.


OMG, no kidding...I hate spiders even more now... :P
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Frenchfry

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Re: Health news
« Reply #27 on: September 03, 2012, 01:50:40 AM »

Happiness Gene Found In Women
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This is what I see when I visit:

"Sorry Frenchfry, you are banned from posting and sending personal messages on this forum.
This ban is not set to expire."

No emails, no warnings, no communication whatsoever...just that ban

May be what happened to the other libs as well.

I guess disabling the report to admin link only on the lib side was indicative of the slanted games they play.

Enjoy your spoon-fed Faux News type right-wing echo-chamber.

Edited to add:

This is the only way to answer some of the questions posed:

1) I did nothing to warrant the banishment, it's political.

2) It's the router that's blocked but considering all the nonsense right-wing games being played by those running the site...it's just not worth it to bypass the banishment block.

3) The moron stalkers from MT contemplating a visit will be considered a threat and can expect to have a bad day if they act upon those idiotic thoughts.

bumfunkegypt@live.com

Frenchfry

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Re: Health news
« Reply #28 on: September 08, 2012, 03:02:22 PM »

Drink To Your Heart's Content -- If It's Nonalcoholic
Wine lovers, get ready for a buzz kill. A new study has found that drinking two glasses of red wine a day can help lower blood pressure and reduce the risk of cardiovascular disease -- but only if the alcohol has been removed.

>snip<

People who wish to abstain from alcohol completely -- and anyone under 21 years of age -- should note that beverages labeled "non-alcoholic" aren't completely alcohol-free. By law, they're allowed to contain up to half a percent of alcohol by volume. A drink that truly has no alcohol is labeled "alcohol free."

More here:
http://abcnews.go.com/Health/Diet/red-wine-minus-alcohol-lower-blood-pressure-study/story?id=17173121
Logged
This is what I see when I visit:

"Sorry Frenchfry, you are banned from posting and sending personal messages on this forum.
This ban is not set to expire."

No emails, no warnings, no communication whatsoever...just that ban

May be what happened to the other libs as well.

I guess disabling the report to admin link only on the lib side was indicative of the slanted games they play.

Enjoy your spoon-fed Faux News type right-wing echo-chamber.

Edited to add:

This is the only way to answer some of the questions posed:

1) I did nothing to warrant the banishment, it's political.

2) It's the router that's blocked but considering all the nonsense right-wing games being played by those running the site...it's just not worth it to bypass the banishment block.

3) The moron stalkers from MT contemplating a visit will be considered a threat and can expect to have a bad day if they act upon those idiotic thoughts.

bumfunkegypt@live.com

Frenchfry

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Re: Health news
« Reply #29 on: September 10, 2012, 02:18:41 AM »

Reseachers Find Coffee Helps Neck And Shoulder Pain Caused By Sitting At A Desk
Logged
This is what I see when I visit:

"Sorry Frenchfry, you are banned from posting and sending personal messages on this forum.
This ban is not set to expire."

No emails, no warnings, no communication whatsoever...just that ban

May be what happened to the other libs as well.

I guess disabling the report to admin link only on the lib side was indicative of the slanted games they play.

Enjoy your spoon-fed Faux News type right-wing echo-chamber.

Edited to add:

This is the only way to answer some of the questions posed:

1) I did nothing to warrant the banishment, it's political.

2) It's the router that's blocked but considering all the nonsense right-wing games being played by those running the site...it's just not worth it to bypass the banishment block.

3) The moron stalkers from MT contemplating a visit will be considered a threat and can expect to have a bad day if they act upon those idiotic thoughts.

bumfunkegypt@live.com
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