My husband has sinus issues a lot and swears by Tylenol Sinus Severe Congestion. Then again, Tylenol is the only otc pain reliever hes allowed to take because of his Crohns so I dont know how it is compared to the others. If you try it, he claims the regular tylenol sinus isnt as good it has to be the severe congestion one (behind the pharmacy counter of course- **** meth heads)